supplements taken in much larger amounts than the body requires.
4. Niacin — Vitamin B3
Niacin is an essential B vitamin, but high doses of nicotinic acid have also been used medically to influence cholesterol levels.
At nutritional doses, niacin is not normally associated with liver damage.
At pharmacological doses, however, it can cause elevations in liver enzymes and, in some cases, clinically significant liver injury.
Certain sustained- or extended-release formulations have been particularly associated with liver toxicity when used improperly.
Possible warning signs can include:
- unusual fatigue
- persistent nausea
- pain
