Amlodipine belong to a class of drugs known as dihydropyridines. They work by blocking L-type calcium channels in the heart and blood vessels, helping to lower blood pressure and reduce chest pain.
However, researchers found that high doses of Nifedipine may excessively shorten the electrical activity (action potential) of heart cells. This can create instability in heart rhythms and increase the risk of dangerous arrhythmias, which can lead to cardiac arrest.
Laboratory experiments confirmed that Nifedipine had a stronger effect on shortening these electrical signals compared to Amlodipine, which may
