The main groups of drugs that might lead to dementia over time

GABA (gamma-aminobutyric acid), which is the main inhibitory (calming) chemical in the brain. While effective for short-term crisis management, taking them long-term fundamentally slows down the central nervous system. Chronic use has been consistently linked in several large-scale studies to an increased risk of dementia, potentially because they interfere with the deep sleep cycles necessary for memory consolidation and disrupt the overall architecture of brain activity.

  1. Proton Pump Inhibitors (PPIs)