GABA (gamma-aminobutyric acid), which is the main inhibitory (calming) chemical in the brain. While effective for short-term crisis management, taking them long-term fundamentally slows down the central nervous system. Chronic use has been consistently linked in several large-scale studies to an increased risk of dementia, potentially because they interfere with the deep sleep cycles necessary for memory consolidation and disrupt the overall architecture of brain activity.
- Proton Pump Inhibitors (PPIs)